01 Nov 2018
By webadmin@macmdaz.com

Improve Diabetes Health With These 7 Must-Dos

Chronic Pain Conditions, Therapies & Treatments, , ,
By Riva Greenberg, Special to Everyday Health Medically Reviewed by Kelly Kennedy, RD A passionate diabetes patient-expert shares small but powerful changes that can help people with diabetes lead a happier, healthier life. Each year, we spend upward of a dozen hours with our healthcare providers, leaving more than 8,700 hours that we must take care of our diabetes. The decisions we make every day, such as whether to follow a healthy diet, make time to be active, adhere to our medication schedule, implement lifestyle changes to improve our lab results, and maintain a positive attitude — can have a major impact on our…
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29 Aug 2018
By webadmin@macmdaz.com

Low Vitamin D linked to Peripheral Neuropathy

Chronic Pain Conditions, Chronic Pain News, ,
Recent studies have reported that patients with Type 2 diabetes and diabetic peripheral neuropathy showed lower Vitamin D levels than patients without T2 diabetes or peripheral neuropathy. Some studies also found including a vitamin D supplementation could help improve painful neuropathic symptoms, which suggests vitamin D could have a role in diabetic peripheral neuropathy.  Low Vitamin D linked to Diabetic Peripheral Neuropathy Patients with type 2 diabetes and painful diabetic peripheral neuropathy had significantly lower 25-hydroxyvitamin D levels compared with healthy volunteers and patients with type 2 diabetes without neuropathy or with painless neuropathy, according to data published in Diabetic Medicine.…
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17 Jul 2017
By webadmin@macmdaz.com

Nerve Decompression Potentially Beneficial in Diabetic Neuropathy

Chronic Pain Conditions, Peripheral Neuropathy, Therapies & Treatments, , ,
This article is part of Endocrinology Advisor's coverage of the American Diabetes Association's 77th Scientific Sessions (ADA 2017), taking place in San Diego, CA. Our staff will report on medical research and technological advances in diabetes and diabetes education, conducted by experts in the field. Check back regularly for more news from ADA 2017. Results of research presented at the 77th American Diabetes Association Scientific Sessions demonstrated that patients with painful diabetic neuropathy who underwent nerve decompression or sham surgery had greater reductions in pain when compared with patients who did not receive surgery. The researchers conducted a randomized, controlled,…
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05 Dec 2016
By webadmin@macmdaz.com

Diabetic Peripheral Neuropathy Management

Peripheral Neuropathy, , , ,
Diabetic peripheral neuropathy affects approximately 60-70% of diabetic patients and a total of 347 million people worldwide.1 This complication is not only associated with painful symptoms, but can also lead to significant consequences such as paresthesia, loss of sensation, ulcers, osteomyelitis, gangrene, foot deformities, and amputation. Common symptoms of diabetic peripheral neuropathy are listed in Table 1. Because the symptoms and complications of diabetic peripheral neuropathy can lead to a significant decrease in a patient's quality of life, it is important to evaluate the effectiveness of the various treatment options available in the management of diabetic peripheral neuropathy. Unfortunately, treating…
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27 Jun 2016
By webadmin@macmdaz.com

Buprenorphine Patches in Diabetic Peripheral Neuropathy

Chronic Pain Conditions, Chronic Pain News, Nerve Pain, ,
Transdermal buprenorphine may be an effective therapy for diabetic peripheral neuropathic pain (DPNP). However the treatment was associated with a high rate of adverse events, mostly nausea and/or vomiting. The findings come from a newly published multi-center, randomized, double-blind, placebo-controlled, parallel-group trial. Ninety-three patients with type 1 or 2 diabetes were enrolled and received either buprenorphine (5μg/h) or placebo patches. All the patients had been experiencing moderate to severe DPNP for a minimum of 6 months on maximal tolerated conventional therapy. The dose was titrated to effect to a maximum of 40μg/h for the study. Results showed that of those…
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14 Mar 2016
By webadmin@macmdaz.com

Intramuscular Injection of Vitamin D may Relieve DPN

Peripheral Neuropathy, Therapies & Treatments, , , , ,
In patients with painful diabetic neuropathy, a single high-dose intramuscular injection of vitamin D appears to confer a significant reduction in symptoms, according to study data. Rayaz A. Malik, MBChB, PhD, professor of medicine at Weill Cornell Medicine in Qatar, and colleagues evaluated 143 adults (mean age, 52 years) with type 1 or type 2 diabetes to determine the effect of a high-dose intramuscular injection of vitamin D (600,000 IU) on painful diabetic neuropathy. Participants were evaluated at baseline and on four subsequent visits every 5 weeks, with follow-up visits taking place at 4 to 6 weeks (visit 2), 8…
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08 Feb 2016
By webadmin@macmdaz.com

Central Nervous System May Contribute to DPN

Chronic Pain News, Peripheral Neuropathy, , ,
One of the key contributors to peripheral nerve disease in patients with diabetes is the central nervous system (CNS), a new report suggests. Published in the journal Pain, the study, conducted by Dr Solomon Tesfaye of Sheffield (UK) Teaching Hospitals NHS Foundation Trust and colleagues found changes within the central nervous system (CNS) were associated with the development of diabetic peripheral neuropathy (DPN), according to a press release. According to the release, about 25% of people with diabetes have symptoms of DPN, including progressive and severe pain and insensitivity to trauma, leading to an increased risk of foot ulcers, infections and…
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21 Oct 2015
By webadmin@macmdaz.com

Capsaicin Patch for Diabetic Neuropathic Pain

Chronic Pain Conditions, Peripheral Neuropathy, Therapies & Treatments, ,
Currently in the United States, capsaicin patches are approved for the treatment of postherpetic neuralgia, however they are not approved for diabetic neuropathic pain. In previous studies, capsaicin patches have demonstrated non-inferior efficacy to pregabalin in peripheral neuropathic pain, with faster onset of action, fewer systemic side effects, and greater treatment satisfaction. Therefore, researchers set out to evaluate the efficacy and safety of capsaicin patch compared to placebo in patients with painful diabetic peripheral neuropathy. Researchers conducted a phase III, multi-center, double-blinded, placebo-controlled, 12-week study, which included 369 patients with painful, distal, symmetrical, sensorimotor diabetic polyneuropathy, which lasted at least…
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28 Sep 2015
By webadmin@macmdaz.com

Surgical Decompression For Compression Neuropathy Offers Many Advantages

Chronic Pain Conditions, Nerve Pain, Peripheral Neuropathy, ,
Surgical decompression can offer long-lasting pain relief and restore sensation in diabetic patients with peripheral neuropathy, leading to an improved quality of life. That was the word from Stephen L. Barrett, DPM, an adjunct professor at Midwestern University College of Health Sciences, Podiatric Medicine Program and founder of Barrett Foot & Ankle in Phoenix, Arizona. Dr. Barrett said that surgical decompression has been shown to restore sensation; reduce pain; prevent amputation and ulceration; improve balance and prevent falls; decrease global healthcare costs; and perhaps most importantly, improve the quality of life for diabetic patients with peripheral neuropathy. 1 “Zhang, Li,…
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25 Sep 2015
By webadmin@macmdaz.com

Prediabetes in Peripheral Neuropathy

Chronic Pain Conditions, Nerve Pain, Peripheral Neuropathy, , ,
Peripheral neuropathy may be more common in patients with prediabetes than previously thought, and early interventions may be warranted in this patient population, according to researchers from the University of Utah. Currently, 86 million adults, more than one in three U.S. adults, have prediabetes, according to CDC estimates. Without weight loss and moderate physical activity, 15% to 30% of these people will develop full-blown type 2 diabetes within 5 years.1 These numbers emphasize the urgent need to treat and prevent the subsequent complications, including neuropathy, associated with prediabetes. Fortunately, researchers are on their way to learning more about the relationship…
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