28 Aug 2017
By webadmin@macmdaz.com

Diabetic Peripheral Neuropathy In Young Adults

Peripheral Neuropathy, , ,
Long-term uncontrolled glycemic levels primary cause of complication in diabetes, such as diabetic peripheral neuropathy. There is a gradual increase in incidence of type 1 diabetes (T1D) and type 2 diabetes (T2D) among the U.S. youth population. Studies show that if this continues, diabetes prevalence among the youth population will triple within three decades. One of the most distressing complications of chronic diabetes is diabetic peripheral neuropathy and contributes to significant disability and diminished quality of life. It has been well-researched and documented among the adult population but not so with the adolescents and young adults in the U.S. Prevalence…
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05 Dec 2016
By webadmin@macmdaz.com

Diabetic Peripheral Neuropathy Management

Peripheral Neuropathy, , , ,
Diabetic peripheral neuropathy affects approximately 60-70% of diabetic patients and a total of 347 million people worldwide.1 This complication is not only associated with painful symptoms, but can also lead to significant consequences such as paresthesia, loss of sensation, ulcers, osteomyelitis, gangrene, foot deformities, and amputation. Common symptoms of diabetic peripheral neuropathy are listed in Table 1. Because the symptoms and complications of diabetic peripheral neuropathy can lead to a significant decrease in a patient's quality of life, it is important to evaluate the effectiveness of the various treatment options available in the management of diabetic peripheral neuropathy. Unfortunately, treating…
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14 Mar 2016
By webadmin@macmdaz.com

Intramuscular Injection of Vitamin D may Relieve DPN

Peripheral Neuropathy, Therapies & Treatments, , , , ,
In patients with painful diabetic neuropathy, a single high-dose intramuscular injection of vitamin D appears to confer a significant reduction in symptoms, according to study data. Rayaz A. Malik, MBChB, PhD, professor of medicine at Weill Cornell Medicine in Qatar, and colleagues evaluated 143 adults (mean age, 52 years) with type 1 or type 2 diabetes to determine the effect of a high-dose intramuscular injection of vitamin D (600,000 IU) on painful diabetic neuropathy. Participants were evaluated at baseline and on four subsequent visits every 5 weeks, with follow-up visits taking place at 4 to 6 weeks (visit 2), 8…
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08 Feb 2016
By webadmin@macmdaz.com

Central Nervous System May Contribute to DPN

Chronic Pain News, Peripheral Neuropathy, , ,
One of the key contributors to peripheral nerve disease in patients with diabetes is the central nervous system (CNS), a new report suggests. Published in the journal Pain, the study, conducted by Dr Solomon Tesfaye of Sheffield (UK) Teaching Hospitals NHS Foundation Trust and colleagues found changes within the central nervous system (CNS) were associated with the development of diabetic peripheral neuropathy (DPN), according to a press release. According to the release, about 25% of people with diabetes have symptoms of DPN, including progressive and severe pain and insensitivity to trauma, leading to an increased risk of foot ulcers, infections and…
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16 Nov 2015
By webadmin@macmdaz.com

Brain discovery leads to new treatments for neuropathy

Chronic Pain Conditions, Peripheral Neuropathy, Therapies & Treatments, , , ,
Peripheral neuropathy is a debilitating condition for which there are few effective treatments, mainly because we do not fully understand the underlying molecular mechanisms, say researchers whose latest discovery appears to shed new light in this area. The team, from McGill University in Montreal, Canada, reports the discovery in The Journal of Neuroscience. They hope the findings will lead to new research to help patients suffering from peripheral neuropathy or neuropathic pain. According to the National Institutes of Health, around 20 million people in the US have some form of peripheral neuropathy - trauma or disease damage to the peripheral…
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02 Nov 2015
By webadmin@macmdaz.com

Hormones Therapy: Newest Pain Care Advance

Chronic Pain Conditions, Nerve Pain, Therapies & Treatments, , , , ,
Severe, uncontrolled pain may exhaust the adrenal gland, resulting in low levels of pregnenolone and cortisol. While adequate pain control will usually normalize serum hormone levels, opioid-induced suppression of the system may require additional treatment. The effect of severe, persistent pain on the hormone system is profoundly negative.1-5 If the patient’s hormone system is not kept homeostatic and balanced, the patient with pain will rapidly age and deteriorate. Episodic excess of cortisol in the blood, which occurs during pain flares, is particularly deleterious. Consequently, the achievement of hormonal balance—not too high or too low—has to be a primary goal of…
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23 Sep 2015
By webadmin@macmdaz.com

The Four Types of Diabetic Neuropathy

Chronic Pain Conditions, Nerve Pain, Peripheral Neuropathy, , , , ,
Most of us associate peripheral neuropathy with diabetes. What might be a surprise is that there are three other forms of neuropathy that are also common to diabetics. Diabetic neuropathy is the result of prolonged periods of excess glucose in the blood damaging fragile nerve fibers. Hyperglycemia also damages the walls of the many blood vessels in the body, including the capillaries that provide the blood supply that supports the nervous system. Finally, high glucose levels interfere with the ability of the nerves to send signals. Taken together, this triad of damage causes first numbness, then extreme pain, in the…
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