Neuropathy Awareness Week

May 5th thru the 12th is National Neuropathy Awareness Week. Neuropathy is a chronic condition that affects millions of people in America. While there is no cure for neuropathy, there are ways to manage the pain associated with it. Many groups including the Foundation for Peripheral Neuropathy and the American Health Council help patients dealing with pain find additional resources such as mental health guides for managing pain. As well as garnering support for research funding to learn more about peripheral neuropathy. So this Neuropathy Awareness week, take time to learn more about this condition and how it can affect…
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Neuropathy And Chronic Back Pain

Neuropathic pain originates in the nerves; and can be thought of as similar to static on a telephone line. Neuropathy happens when nerves become damaged or dysfunctional because of an injury or trauma. It's considered a chronic condition. Neuropathic pain is distinct from other types of pain. If a person breaks a bone, pain signals are carried via nerves from the site of the trauma to the brain. With neuropathic pain, however, pain signals originate in the nerves themselves. How Neuropathic Pain Develops In many cases, the nerves become damaged or dysfunctional after responding to an injury or trauma, causing…
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Light Therapy to Treat Neuropathic Pain

For someone with peripheral neuropathy, even the slightest touch can cause burning, stinging or shooting pain, usually in the hands or feet. The pain is caused when the peripheral nervous system is damaged by diabetes, shingles, chemotherapy or some other medical condition. About 8% of adults worldwide suffer from some form of neuropathy. Medications prescribed to dull the pain – such as opioids, anti-depressants or gabapentin (Neurontin) -- often prove to be ineffective, don’t last long or have unwanted side effects. Scientists in Italy have now discovered an experimental way to treat neuropathy that provides pain relief for weeks at…
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Researchers ‘Hack’ Into the Brain’s Electrical Signals

A team from University of Chicago figured out a new way to use light and nanotechnology to "hack" into brain function. For decades, neuroscientists and engineers have wanted to uncover the secrets of the human brain. Pop culture and science fiction films only serve to play into the understanding of the idea that the human brain can be 'hacked'. But one team of researchers might have actually gotten the world significantly closer to manipulating how our brain functions. Researchers from the University of Chicago used tiny, light-powered silicon wires to reshape how the brain responds. One day, the process could…
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Pain Receptors Migrating may cause Chronic Pain

A study led by Columbia University Medical Center (CUMC) has shown that chronic pain may occur when pain receptors migrate from the nerve cell's surface to the cell's inner chambers, out of the reach of current pain medications. The discovery, in rodents, may lead to the development of a new class of medications for chronic pain that is more potent and less prone to side effects than currently available pain treatments. The study was published online today in the journal Science Translational Medicine. An estimated 20 percent of people have chronic pain at some point. Currently available therapies for chronic…
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Nerve Decompression Potentially Beneficial in Diabetic Neuropathy

This article is part of Endocrinology Advisor's coverage of the American Diabetes Association's 77th Scientific Sessions (ADA 2017), taking place in San Diego, CA. Our staff will report on medical research and technological advances in diabetes and diabetes education, conducted by experts in the field. Check back regularly for more news from ADA 2017. Results of research presented at the 77th American Diabetes Association Scientific Sessions demonstrated that patients with painful diabetic neuropathy who underwent nerve decompression or sham surgery had greater reductions in pain when compared with patients who did not receive surgery. The researchers conducted a randomized, controlled,…
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Blocking Intracellular Glutamate May Halt Neuropathic Pain

Experiments to block receptors deep within spinal neurons, metabotropic glutamate 5 receptors (mGluR5), may open the door to more effective treatments for neuropathic pain. Understanding how the body processes pain is essential to understanding how to better treat it. Aiding in that understanding has been intense research on one of the key players that transmit nociceptive information through the body. G-protein-couple receptors (GPCRs) play a critical role in various bodily functions, including as a mediator of neuroplasticity underlying chronic pain.  One specific receptor, metabotropic glutamate 5 receptor (mGluR5), is heavily abundant in the dorsal horn (DH),1,2 prime real estate for…
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Inherited Neuropathy: New Cause Identified

Neurology researchers link mutations in myelin protein to Charcot-Marie-Tooth Disease, an inherited neuropathy. PHILADELPHIA - Charcot-Marie-Tooth Disease (CMT) is in the family of inherited neuropathy, of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most of which have to date been linked to a small set of causative genes. New research from the department of Neurology at the Perelman School of Medicine at the University of Pennsylvania and the Children's Hospital of Philadelphia recently spanned the globe to uncover a new genetic cause of CMT1. Their findings are published online…
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Easing Pain: complementary therapies

Psychologists are exploring complementary therapies and integrated approaches to better treat the complex problem of chronic pain. If cancer is "the emperor of all maladies," as physician and author Siddhartha Mukherjee wrote, chronic pain may be the empress, affecting 100 million people in the United States and costing up to $630 billion each year in treatments and lost productivity, according to a 2011 report from the Institute of Medicine (IOM). For many, pain digs in and cuts deep. A 2012 survey funded by the National Center for Complementary and Integrative Health (NCCIH) found that some 25.3 million U.S. adults —…
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Autonomic neuropathy in diabetic neuropathy

Autonomic neuropathy in diabetic neuropathy has an effect on hypoglycemia symptoms. Autonomic neuropathy is when the nerves that control bodily functions become damaged. Blood pressure, temperature control, digestion, bladder function and sexual function can all be affected by autonomic neuropathy. Normally, nerves send messages to the brain and other organs to ensure they function properly. Because autonomic neuropathy damages these nerves, signals cannot be properly sent, thus causing complications and loss of control. The most common cause of autonomic neuropathy is diabetes but even infections have been shown to cause it. Medications, too, can contribute to autonomic neuropathy. Diabetes, a…
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