Neuropathic Pain from Peripheral Nerve Injury

Chronic Pain News, Nerve Pain, Peripheral Neuropathy
Neuropathic pain is a complex, chronic pain state that usually is accompanied by tissue injury. With neuropathic pain, the nerve fibers themselves may be damaged, dysfunctional, or injured. These damaged nerve fibers send incorrect signals to other pain centers. The impact of nerve fiber injury includes a change in nerve function both at the site of injury and areas around the injury. One example of neuropathic pain is called phantom limb syndrome.This rare condition occurs when an arm or a leg has been removed because of illness or injury, but the brain still gets pain messages from the nerves that originally carried impulses from the missing limb. These nerves now misfire and cause pain. Causes of Neuropathic Pain Neuropathic pain often seems to have no obvious cause; but, some common…
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Electrical Nerve Stimulation Device Prevents Migraine

Chronic Pain News, Nerve Pain, Spinal Cord Stimulation
Study shows 81% reduction in number of migraine days per month with electrical nerve stimulation In a new study, Cefaly, the first FDA-approved transcutaneous electrical nerve-stimulation device for use before the onset of migraine pain, provided relief for 81% of migraine patients who used it. The study, conducted in Italy, enrolled 24 patients with migraine without aura who were experiencing a low number of attacks per month and who had taken migraine-preventive drugs. The primary outcome measures were the reductions in migraine attacks and in the number of migraine days per month. The investigators also analyzed the percentage of patients with at least a 50% reduction in the rate of monthly migraine attacks and in the number of migraine days. Secondary outcome measures included the reduction of headache severity during…
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Diabetic Neuropathy: Temporarily Reducing Pain

Chronic Pain Conditions, Chronic Pain News, Peripheral Neuropathy
Painful diabetic neuropathy (PDN) can be relieved for months with a non-viral gene therapy, according to research published in the Annals of Clinical and Translational Neurology. Researchers from Northwestern Medicine administered the non-viral gene therapy or a placebo in order to evaluate the safety and efficacy of a plasmid (VM202) containing 2 human hepatocyte growth factor isoforms given by intramuscular injections in patients with PDN. There were 84 patients included in the study who were randomized to either receive injections of 8 or 16 mg VM202 per leg or placebo. Doses were administered on days zero and 14. The researchers asked the participants to evaluate their mean pain scores measured by a 7 day pain diary. The researchers had secondary objectives in this study, such as assessing quality of life…
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Spinal Cord Cells Control Pain

Chronic Pain Conditions, Chronic Pain News, Nerve Pain
Spinal cord cells are responsible for controlling pain and itch, according to research published in the journal Neuron. Researchers from the University of Zurich used genetically modified viruses to interfere with the functions of neurons in mice in order to investigate how neurons contribute to pain and itch processing. The researchers drew on prior findings from 50 years ago, which had demonstrated “Gate Control Theory” of pain – the idea that inhibitory nerve cells in the spinal cord could determine whether a pain impulse from the periphery (from the foot, for example) is relayed to the brain or suppressed. The researchers found that the spinal cord cells, located specifically in the spinal dorsal horn, use the amino acid glycine as an inhibitory messenger. By disabling the neurons, which released glycine,…
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Shingles: The Pain and the Misery

Chronic Pain Conditions, Chronic Pain News
Shingles is currently on the rise especially among those aged 60 and over, it is in essence a "reawakening" of the chickenpox virus. Never fully discharged from the body, this virus lies inactive for years and reactivates when immunity is weakened, traveling through the nerve pathways to your skin and producing shingles. The first symptoms appear usually on either the left or right side of the torso, starting with a burning pain, tingling and then erupting in a red rash in the painful area At first, the rash appears similar to hives but the patches then develop into fluid-filled blisters that break open and crust over. Unlike other allergic rashes that cause itching, the patient will feel pain, which might be extreme in the affected dermatome, with sensations that are…
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5 Natural Neuropathy Treatments

5 Natural Neuropathy Treatments

Chronic Pain News
For those dealing with the painful effects of nerve damage, finding alternative or natural treatments can open new doors in the search for relief. While prescription medications simply mask the pain, natural neuropathy treatments often treat the underlying causes. In many cases, this can result in more lasting relief for the sufferer. Many people have experienced beneficial results by following complementary or alternative medicine. When done as a part of a multi-pronged treatment approach, natural methods have shown great promise. We’ve pulled together a list of 5 natural treatments for treating neuropathy that we’ve seen provide relief for others. Lets take a look: 5 Natural Neuropathy Treatments 1. Acupuncture Acupuncture involves insertion of thin needles into the various points in the body. Though it can seem a bit unsettling to have someone…
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Tour de Hero – Blood Donation

Chronic Pain News
Over the weekend Dr. Castillo participated in Tour de Hero, an annual bike race established to raise awareness and recruit blood donors in Arizona leading into the holiday season. The Tour de Hero bike ride was established to raise awareness and recruit blood donors for Arizona patients leading into the holiday season.  Ask your friends, family and co-workers to donate between Nov. 1 and Jan. 10 at a United Blood Services donor center.  You may also donate on your own behalf, as well as secure sponsors to give monetary donations to support United Blood Services’ donor recruitment efforts.  In appreciation for blood donors and sponsors, riders receive discounted Tour de Hero rider fees and earn one ticket for great raffle prizes for each donor recruited. Simply download the Donor Sponsor Card with all the…
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