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That a finger can distinguish the texture of satin from suede is an exquisite sensory discrimination. Largely relying on small sensory organs in the fingertips called Merkel discs containing Merkel Cells. Jianguo Gu, Ph.D., of the University of Alabama at Birmingham, has now unraveled how the sensory information is processed in the Merkel discs. As […]
Researchers from California discover the key to simplifying the creation of engineered bones: adenosine. This naturally occurring molecule can be injected into bone tissue to coax human pluripotent stem cells to regenerate. REGENERATING BONE TISSUE The incidence of bone disorders, particularly in populations where aging is tied to rising obesity rates and poor physical activity.
Applications from regenerative medicine to gene therapy as well as antiviral therapeutic interventions emphasize self-healing possibilities. Therapeutic Interventions Emphasize Self-Healing Therapeutic interventions of various kinds try to improve the body’s capacity to defend, repair, and even cure itself. Interventions that attempt to enhance self-healing span cell-based therapy, gene therapy, small molecule drugs, biologics, and tissue
Recently scientists have found a substance that activates pain along the central nervous system. This substance is also able to decrease pain in the peripheral nervous system. It was named Substance P. And may be the reason many pain management drugs appear to be successful amid laboratory tests. As well as unsatisfactory in real-life circumstances. The
‘‘Get your health from the farm, not from the pharmacy.’’ That’s not necessarily what you’d expect to hear at an international medical conference. Especially one attended by some of the biggest names in the world of medicine and nutrition. Nor do you expect this declaration to be received with clapping, whooping and cheering from a
Dr. Brian M. Ilfeld, MD, MS, feels this strongly about the potential for ultrasound-guided percutaneous peripheral nerve stimulation. It’s a technology that he says has the potential to forever change the way anesthesiologists treat acute postoperative pain. He discussed the results of a prospective feasibility study. As well as the potential for the technology’s future—at
A therapeutic intervention involving confronting and expressing emotional and traumatic experiences shows greater improvement in fibromyalgia pain. When compared with conventional cognitive-behavioral therapy (CBT), randomized trial results show. It was also linked to significant pain reductions when offered as a one-time intervention in the primary care setting, researchers report. “Current evidence-based psychological interventions for fibromyalgia,
What is neuroinflammation and why does it cause severe burning pain even when there seems to be no injury? Let me explain it as simply as I can. Say you sprain your ankle. Your ankle then hurts, swells, discolors, and the pain limits use. The swelling occurs because of “healing” chemicals that move into the
Transdermal buprenorphine may be an effective therapy for diabetic peripheral neuropathic pain (DPNP). However the treatment was associated with a high rate of adverse events, mostly nausea and/or vomiting. The findings come from a newly published multi-center, randomized, double-blind, placebo-controlled, parallel-group trial. Ninety-three patients with type 1 or 2 diabetes were enrolled and received either
A toxin isolated from the Togo starburst tarantula provides new insights into pain mechanisms and could lead to new treatments for irritable bowel syndrome. With their large, hairy bodies and long legs, tarantulas are an arachnophobe’s worst nightmare. For pain researchers, however, these outsized spiders are a dream come true: Their venom contains a cocktail
