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One of the key contributors to peripheral nerve disease in patients with diabetes is the central nervous system (CNS), a new report suggests. Published in the journal Pain, the study, conducted by Dr Solomon Tesfaye of Sheffield (UK) Teaching Hospitals NHS Foundation Trust and colleagues found changes within the central nervous system (CNS) were associated […]
Peripheral nerve stimulation (PNS) is an effective long-term treatment for managing chronic intractable headaches, suggests research published in Pain Physician. In this retrospective study, peripheral nerve stimulation reduced mean headache severity on the 11-point Numeric Rating Schedule (NRS) by nearly 50% within one-month post implantation. After 12 months, headache severity scores decreased by at least 50%
Peripheral neuropathy is a debilitating condition for which there are few effective treatments, mainly because we do not fully understand the underlying molecular mechanisms, say researchers whose latest discovery appears to shed new light in this area. The team, from McGill University in Montreal, Canada, reports the discovery in The Journal of Neuroscience. They hope
Severe, uncontrolled pain may exhaust the adrenal gland, resulting in low levels of pregnenolone and cortisol. While adequate pain control will usually normalize serum hormone levels, opioid-induced suppression of the system may require additional treatment. The effect of severe, persistent pain on the hormone system is profoundly negative.1-5 If the patient’s hormone system is not
Currently in the United States, capsaicin patches are approved for the treatment of postherpetic neuralgia, however they are not approved for diabetic neuropathic pain. In previous studies, capsaicin patches have demonstrated non-inferior efficacy to pregabalin in peripheral neuropathic pain, with faster onset of action, fewer systemic side effects, and greater treatment satisfaction. Therefore, researchers set
CHICAGO — As many as 50% of patients undergoing chemotherapy for cancer experience chemotherapy induced peripheral neuropathy. But most cases go undiagnosed, according to results presented at the American Neurological Association 2015 Annual Meeting in Chicago. Noah A. Kolb, MD, of the University of Utah, and colleagues studied the frequency of chemotherapy-induced peripheral neuropathy and
DEAR MAYO CLINIC: I was diagnosed with spinal stenosis about 12 years ago. I haven’t had many symptoms over the years, but about six months ago I started noticing increasing discomfort in my legs. Is surgery an option to treat spinal stenosis? If not, what else can I do? The leg pain is making it
Logan resident Dawn Carter’s life changed in January 2015 following an accidental fall down a flight of stairs. Originally diagnosed with just a concussion, complications from the injury now cause Carter to experience chronic nerve pain and migraines, in addition to seizures and memory loss. “There is really nothing (my doctors) can do about my
Neuropathic pain is a complex, chronic pain state that usually is accompanied by tissue injury. With nerve pain, the nerve fibers themselves may be damaged, dysfunctional, or injured. These damaged nerve fibers send incorrect signals to other pain centers. The impact of nerve fiber injury includes a change in nerve function both at the site
Natural Treatments can help Peripheral Neuropathy Millions of Americans suffer from the painful affects of peripheral neuropathy pain. Peripheral neuropathy, a result of damage to your peripheral nerves, often causes weakness, numbness and pain, usually in your hands and feet. It can also affect other areas of your body. Peripheral neuropathy can result from traumatic
