A study led by Columbia University Medical Center (CUMC) has shown that chronic pain may occur when pain receptors migrate from the nerve cell’s surface to the cell’s inner chambers, out of the reach of current pain medications. The discovery, in rodents, may lead to the development of a new class of medications for chronic…
DetailsThis article is part of Endocrinology Advisor’s coverage of the American Diabetes Association’s 77th Scientific Sessions (ADA 2017), taking place in San Diego, CA. Our staff will report on medical research and technological advances in diabetes and diabetes education, conducted by experts in the field. Check back regularly for more news from ADA 2017. Results…
DetailsA study by an international team of researchers has found that a class of drugs used for other indications, such as nearsightedness, incontinence, and peptic ulcers, may also prevent neuropathy. Lead investigator Dr. Paul Fernyhough of the University of Manitoba said: “An exciting aspect of the work is that these are new uses for old…
DetailsClinical results reported at the 2017 North American Neuromodulation Society meeting show that peripheral nerve stimulation provides meaningful relief for people suffering from post-stroke shoulder pain (PSSP). Post stroke shoulder pain is experienced by anywhere between 30 and 70 percent of stroke sufferers. Dr. Porter McRoberts, a trained Physiatrist and Interventional Spine and Pain Management…
DetailsAbstract and Introduction Abstract Microvascular complications of diabetes include eye disease, kidney disease, and peripheral and/or autonomic neuropathy. This study illustrates the importance of early screening and detection of microvascular complications, while also focusing on treatment guidelines and indications for specialist referral. Introduction Diabetes mellitus (DM) is a chronic disease that is classified, based on…
DetailsFunctional abdominal pain syndrome (FAPS) is a functional gastrointestinal disorder, which involves chronic or frequent pain that does not result from a specific, identifiable cause. Symptoms The primary symptom of FAPS is abdominal pain. The pain can often be very severe and impact the quality of life of patients significantly. This can even disrupt their…
DetailsThe distinction between a headache and a migraine can be hard to define. For those who have never been affected, the distinction between a headache and migraines can be hard to define. Headaches affect the head, are caused by stress, exhaustion, et cetera, and are painful [1]. Migraines are a type of headache that display…
DetailsNearly every advance in modern medicine, from diagnosis to treatment, has benefited from animal studies. Basic research has made vital contributions to all aspects of medical care, including our understanding of pain pathophysiology. However, the applicability of these findings to humans remains limited. “Translation from animal to human is hindered by many obstacles, in particular…
DetailsDiabetic peripheral neuropathy affects approximately 60-70% of diabetic patients and a total of 347 million people worldwide.1 This complication is not only associated with painful symptoms, but can also lead to significant consequences such as paresthesia, loss of sensation, ulcers, osteomyelitis, gangrene, foot deformities, and amputation. Common symptoms of diabetic peripheral neuropathy are listed in…
DetailsThat a finger can distinguish the texture of satin from suede is an exquisite sensory discrimination largely relying on small sensory organs in the fingertips called Merkel discs. Jianguo Gu, Ph.D., of the University of Alabama at Birmingham, has now unraveled how the sensory information is processed in the Merkel discs and further conveyed to…
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