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Functional Abdominal Pain Syndrome

Functional abdominal pain syndrome (FAPS) is a functional gastrointestinal disorder, which involves chronic or frequent pain that does not result from a specific, identifiable cause.

Symptoms

The primary symptom of FAPS is abdominal pain. The pain can often be very severe and impact the quality of life of patients significantly. This can even disrupt their normal daily routine due to inability to take part in certain activities. It can also have a financial impact on their wellbeing and may increase levels of stress.

The condition is not usually associated with gastrointestinal symptoms such as diarrhea or constipation, and the findings from imaging and laboratory tests are often unable to explain the cause of the pain.

The pain is actually associated with changes in the sensitivity to nerve impulses between the gut and the brain. It is, therefore, a functional problem and not associated with abnormal intestinal motility.

It is important to note that the symptoms of FAPS often appear or worsen after certain events, such as an infection, traumatic life events, or significant stress.

Cause

For people with FAPS, there is an alteration in the brain-gut axis and ability of the nervous system to regulate the pain signals for the gastrointestinal tract. As a result, even small stimuli that disturb the intestines can become amplified and lead to severe pain, known as central hypersensitivity.

In some cases, repeated injury to the abdomen may be associated with causing FAPS, due to over-sensitization of the nerve receptors in the area. For example, people who have had multiple abdominal surgeries, recurrent infections or a history of physical or sexual abuse are more likely to be affected by the condition.

Diagnosis

The diagnosis of FAPS typically involves a series of diagnostic tests to identify the cause of the pain. This may include X-rays, ultrasound imaging, computed tomography (CT) scans, endoscopy, and blood tests. For patients with FAPS, these tests are not able to reveal a specific cause of the pain.

It can be helpful for patients to keep a pain diary to record symptoms and possible triggers that may have caused a flare-up of symptoms. Over time, this information can help to identify problematic time and causes of worsened symptoms, which can be helpful when developing management strategies.

By: Yolanda Smith, B.Pharm.

Updated: 08/23/2018

Continue reading the full article from News Medical Life Science

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