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Athletes who complain of deep buttock pain and pain when sitting may have hamstring tendinopathy. Playser with deep, posterior, upper thigh pain may be suffering from high (proximal) hamstring tendon injury as well. Chronic high hamstring tendinopathy is becoming increasing recognized as a causative factor in both sitting and activity-related posterior hip pain.1,2,3 Unlike an […]
Induced pluripotent stem cells (iPSCs) can be generated from adult cells. iPSCs have the potential to develop into any cell type in the human body. These cells hold an enormous therapeutic potential in a variety of conditions. Including but not limited to cardiac diseases, Alzheimer’s, Parkinson’s disease, spinal cord injury, and diabetes. A team of researchers
Transdermal buprenorphine may be an effective therapy for diabetic peripheral neuropathic pain (DPNP). However the treatment was associated with a high rate of adverse events, mostly nausea and/or vomiting. The findings come from a newly published multi-center, randomized, double-blind, placebo-controlled, parallel-group trial. Ninety-three patients with type 1 or 2 diabetes were enrolled and received either
Sacral chordoma is a rare malignant tumor arising from remnants of the notochord. Due to its propensity for recurrence, the treatment of choice is surgical resection. Orthopedic and neurosurgical literature describe bladder dysfunction as prevalent in these patients, specifically urinary incontinence, however urologic literature is lacking in the exact nature of this dysfunction. Thus far,
Researchers Map Full-length Protein Involved in Chronic Pain, with Hopes for Future Therapies Case Western Reserve University School of Medicine researchers have discovered the full-length structure of a protein named Transient Receptor Potential Vanilloid subtype 2 (TRPV2), with implications for the development of new treatments for chronic pain and cancer. The paper, “Structure of the full-length TRPV2 channel by
Okazaki, Japan – When we are in pain, we reach for painkillers as we try to “turn off” the pain. Unfortunately, this does not always work, and this problem has prompted researchers around the world to seek the “main switch” that can promptly and effectively conduct this switching off. Pain comes in many forms; one
Phantom limb pain (PLP) is described as mild to extreme pain in an amputated limb. It was previously thought as a psychological response of patients who underwent amputation, but recent studies reveal scientific evidence of pain sensation that originates from the brain and spinal cord. Although phantom limb pain is often seen in patients with
Neurology researchers link mutations in myelin protein to Charcot-Marie-Tooth Disease, an inherited neuropathy. PHILADELPHIA – Charcot-Marie-Tooth Disease (CMT) is in the family of inherited neuropathy, of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most of which have to date been linked to a small
Pain is a sensation that is triggered in the nervous system. It can be sharp or dull and last for short or long periods. Pain may be localized to a specific area of the body such as the abdomen, chest or back or it can be felt all over the body, such as when a
What is Degenerative Disc Disease? Degenerative Disc Disease (or DDD) is caused by degeneration of the discs in the spinal column. Age can cause this, but most of the time it is cause by some sort of trauma to the spine. People with bulging or herniated disc almost always have this disease, as well as
