TMS Protocol May Be Effective in CRPS
The use of a novel frequency pairing for transcranial magnetic stimulation (TMS) may effectively relieve upper and lower extremity pain associated with complex regional pain syndrome (CRPS), according to a study published in Neuromodulation. The TMS protocol used in this study consisted of initial intermittent theta bursts (ie, burst of three 50-Hz pulses every 200 ms, 2 second-long trains repeated every 10 s, total of 600 pulses, delivered at 70% of the resting motor threshold [RMT]). This was followed by a 10-Hz stimulation (duration, 10 s; intertrain interval, 30 s; total pulses, 2000; delivered at 80% of RMT). Muscle activity was monitored throughout…