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The live varicella-zoster vaccine can effectively prevent shingles in rheumatoid arthritis patients starting treatment with the drug tofacitinib, according to results of 2 recently-published studies in Arthritis & Rheumatology. Shingles causes a painful rash that may appear as a stripe of blisters on the trunk of the body. Pain can persist even after the rash is gone […]
In the wake of mounting overdoses and deaths from the opioids-addiction crisis sweeping across the U.S., drugmakers are racing to come up with safer painkillers. Companies are highly motivated to create alternatives to the $4 billion opioid market. The federal government is cracking down on lax prescriptions that contribute to many thousands of deaths a
Nicotinamide riboside (NR), a type of vitamin B3, may prevent chemotherapy-induced peripheral neuropathy (CIPN), a recent study in animals has shown. Although chemotherapy increases survival rates, it can have serious side effects, including peripheral neuropathy, that affect quality of life.1 “Our findings support the idea that NR could potentially be used to prevent or mitigate
This article is part of Endocrinology Advisor’s coverage of the American Diabetes Association’s 77th Scientific Sessions (ADA 2017), taking place in San Diego, CA. Our staff will report on medical research and technological advances in diabetes and diabetes education, conducted by experts in the field. Check back regularly for more news from ADA 2017. Results
The power of the body to heal itself is amazingly evident in a promising newer treatment known as regenerative stem cell therapy. Which orthopedic surgeon Kevin D. Plancher, MD, founder of Plancher Orthopedics & Sports Medicine, is tapping more frequently to help restore pain-free movement in patients with stubborn knee or shoulder problems. A branch
Applications from regenerative medicine to gene therapy as well as antiviral therapeutic interventions emphasize self-healing possibilities. Therapeutic Interventions Emphasize Self-Healing Therapeutic interventions of various kinds try to improve the body’s capacity to defend, repair, and even cure itself. Interventions that attempt to enhance self-healing span cell-based therapy, gene therapy, small molecule drugs, biologics, and tissue
Induced pluripotent stem cells (iPSCs) can be generated from adult cells. iPSCs have the potential to develop into any cell type in the human body. These cells hold an enormous therapeutic potential in a variety of conditions. Including but not limited to cardiac diseases, Alzheimer’s, Parkinson’s disease, spinal cord injury, and diabetes. A team of researchers
Sacral chordoma is a rare malignant tumor arising from remnants of the notochord. Due to its propensity for recurrence, the treatment of choice is surgical resection. Orthopedic and neurosurgical literature describe bladder dysfunction as prevalent in these patients, specifically urinary incontinence, however urologic literature is lacking in the exact nature of this dysfunction. Thus far,
A toxin isolated from the Togo starburst tarantula provides new insights into pain mechanisms and could lead to new treatments for irritable bowel syndrome. With their large, hairy bodies and long legs, tarantulas are an arachnophobe’s worst nightmare. For pain researchers, however, these outsized spiders are a dream come true: Their venom contains a cocktail
Experiments to block receptors deep within spinal neurons, metabotropic glutamate 5 receptors (mGluR5), may open the door to more effective treatments for neuropathic pain. Understanding how the body processes pain is essential to understanding how to better treat it. Aiding in that understanding has been intense research on one of the key players that transmit
