Diabetic Neuropathy: Temporarily Reducing Pain
Painful diabetic neuropathy (PDN) can be relieved for months with a non-viral gene therapy, according to research published in the Annals of Clinical and Translational Neurology. Researchers from Northwestern Medicine administered the non-viral gene therapy or a placebo in order to evaluate the safety and efficacy of a plasmid (VM202) containing 2 human hepatocyte growth factor isoforms given by intramuscular injections in patients with PDN. There were 84 patients included in the study who were randomized to either receive injections of 8 or 16 mg VM202 per leg or placebo. Doses were administered on days zero and 14. The researchers…