Merkel Cells in the Fingertips

That a finger can distinguish the texture of satin from suede is an exquisite sensory discrimination. Largely relying on small sensory organs in the fingertips called Merkel discs containing Merkel Cells. Jianguo Gu, Ph.D., of the University of Alabama at Birmingham, has now unraveled how the sensory information is processed in the Merkel discs. As well as further conveyed to the ending of a sensory nerve, the start of its journey to the brain. Such molecular understanding about the sensory information transmission between Merkel cells and nerve endings could be radical. And may lay the foundation to treat patients' intense…
Read More

Regenerative Biology: A New Molecule Regenerates Bone Tissue

Researchers from California discover the key to simplifying the creation of engineered bones: adenosine. This naturally occurring molecule can be injected into bone tissue to coax human pluripotent stem cells to regenerate. REGENERATING BONE TISSUE The incidence of bone disorders, particularly in populations where aging is tied to rising obesity rates and poor physical activity. Bone disorders have been increasing steadily— so much so that it is expected to double in the coming years. To date, bone grafts have been the only solution to this problem. But researchers from the University of California in San Diego have now found a…
Read More