Peripheral Neuropathy in Cancer Patients

Identifying the causes of peripheral neuropathy in cancer patients can be difficult. There are many common causes of peripheral neuropathy in cancer patients. Neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system. Peripheral neuropathies arise from disorders associated specifically within the peripheral nervous system. Symptoms of peripheral neuropathy can include numbness, tingling, pins and needles sensations, sensitivity to touch, or muscle weakness. There are multiple causes of peripheral neuropathy in patients with cancer, identifying the culprit may be complicated by a plethora of etiologies. The peripheral neuropathy can originate from the cancer…
Read More

Cervical Nerves

In addition to the seven cervical vertebrae, cervical anatomy features eight cervical nerve roots (C1-C8). These roots branch from the spinal cord and control motor and sensory abilities for different parts of the body. From there each cervical nerve is named based on the lower cervical vertebra that it runs between. As an example, the C6 nerve root runs between the C5 vertebra and the C6 vertebra. Cervical Nerve Functions Each level of the cervical spine actually has two nerve roots—one on each side—that branch off from the spinal cord. Keeping with the aforementioned example at the C5-C6 level, each…
Read More

Leg Pain and Foot Pain Causes

Leg and foot pain can originate from other chronic conditions such as lumbar back pain. The nerves that control muscle functions in the legs are located in the lower back, and that’s where symptoms of leg pain can instigate in some cases. Symptoms of leg pain caused by the lower back conditions can include numbness, tingling, shooting pain, or foot drop. Degeneration in our vertebral spine happens as we age, resulting in lost disc flexibility, and can cause pain to radiate down the leg during movement. Leg and foot pain can be symptoms of lumbar degenerative disc disease, along with…
Read More

Neuropathy And Chronic Back Pain

Neuropathic pain originates in the nerves; and can be thought of as similar to static on a telephone line. Neuropathy happens when nerves become damaged or dysfunctional because of an injury or trauma. It's considered a chronic condition. Neuropathic pain is distinct from other types of pain. If a person breaks a bone, pain signals are carried via nerves from the site of the trauma to the brain. With neuropathic pain, however, pain signals originate in the nerves themselves. How Neuropathic Pain Develops In many cases, the nerves become damaged or dysfunctional after responding to an injury or trauma, causing…
Read More

Shingles Pain Cause Discovered

It is very likely that when you were a child, you had chickenpox, a mostly benign condition that despite making you extremely itchy, required you to miss a week or two of school. While most parents would think their children are safe from the infection after its resolved, what they don’t realize is that it may show up later in life in a painful form called shingles. A constant feature of shingles is neuralgia—intense pain affecting mainly the nerves of the chest and neck, the trigeminal nerve in the fact, and the lower back. New research out of the University of…
Read More

Nerve Decompression Potentially Beneficial in Diabetic Neuropathy

This article is part of Endocrinology Advisor's coverage of the American Diabetes Association's 77th Scientific Sessions (ADA 2017), taking place in San Diego, CA. Our staff will report on medical research and technological advances in diabetes and diabetes education, conducted by experts in the field. Check back regularly for more news from ADA 2017. Results of research presented at the 77th American Diabetes Association Scientific Sessions demonstrated that patients with painful diabetic neuropathy who underwent nerve decompression or sham surgery had greater reductions in pain when compared with patients who did not receive surgery. The researchers conducted a randomized, controlled,…
Read More

Emotional Expression Benefits Chronic Pain

A therapeutic intervention involving confronting and expressing emotional and traumatic experiences shows greater improvement in fibromyalgia pain. When compared with conventional cognitive-behavioral therapy (CBT), randomized trial results show. It was also linked to significant pain reductions when offered as a one-time intervention in the primary care setting, researchers report. "Current evidence-based psychological interventions for fibromyalgia, such as CBT, are relatively weak. We believe, because they do not help patients disclose, target, and resolve their conflicted emotional experiences," senior author Mark Lumley, PhD, professor of psychology at Wayne State University, Detroit, Michigan, told Medscape Medical News. "We have demonstrated, however, that…
Read More

Neuroinflammation: How it causes Chronic Pain

What is neuroinflammation and why does it cause severe burning pain even when there seems to be no injury? Let me explain it as simply as I can. Say you sprain your ankle. Your ankle then hurts, swells, discolors, and the pain limits use. The swelling occurs because of “healing” chemicals that move into the affected area and work to repair any damage. In a typical person, this process is successful and the healing chemicals trigger another set of chemicals to take the healing chemicals away. The swelling and discoloration go away and the person doesn’t have any additional issues…
Read More

Buprenorphine Patches in Diabetic Peripheral Neuropathy

Transdermal buprenorphine may be an effective therapy for diabetic peripheral neuropathic pain (DPNP). However the treatment was associated with a high rate of adverse events, mostly nausea and/or vomiting. The findings come from a newly published multi-center, randomized, double-blind, placebo-controlled, parallel-group trial. Ninety-three patients with type 1 or 2 diabetes were enrolled and received either buprenorphine (5μg/h) or placebo patches. All the patients had been experiencing moderate to severe DPNP for a minimum of 6 months on maximal tolerated conventional therapy. The dose was titrated to effect to a maximum of 40μg/h for the study. Results showed that of those…
Read More

Acupuncture for Diabetes

For people with diabetes, the needle-based therapy known as acupuncture may offer a number of health benefits. Some research shows that acupuncture may help control diabetes by treating insulin resistance, while other studies indicate that this long-practiced form of traditional Chinese medicine may help protect against certain complications commonly linked to diabetes. Acupuncture and Insulin Resistance Insulin resistance occurs when your body fails to use insulin effectively. A hormone produced by the pancreas, insulin is responsible for helping your cells take in glucose (i.e., blood sugar) and use it for energy. In cases of insulin resistance, the cells have trouble absorbing glucose,…
Read More