Capsaicin Patch for Diabetic Neuropathic Pain
Currently in the United States, capsaicin patches are approved for the treatment of postherpetic neuralgia, however they are not approved for diabetic neuropathic pain. In previous studies, capsaicin patches have demonstrated non-inferior efficacy to pregabalin in peripheral neuropathic pain, with faster onset of action, fewer systemic side effects, and greater treatment satisfaction. Therefore, researchers set out to evaluate the efficacy and safety of capsaicin patch compared to placebo in patients with painful diabetic peripheral neuropathy. Researchers conducted a phase III, multi-center, double-blinded, placebo-controlled, 12-week study, which included 369 patients with painful, distal, symmetrical, sensorimotor diabetic polyneuropathy, which lasted at least…